Freeze Dryer Refrigerating System Unit

The single unit double-stage compressor is used as main engine for the system. The compressor is equipped with forced lubrication and crankshaft case heater. Each compressor has its separate refrigerating circulation system, serving the shelf and condenser through heater exchanger or coiled pipe. According to the logic operation, the compressor can cool the shelf directly.
Preserving the refrigerating capacity:
The refrigerating system is powerful enough for the preservation of refrigerating capacity, therefore, it can cope with most of abnormal refrigerating, even under full load, it will not cause to reach the extremity of the system.

Freeze Dryer Shelf Cooling and Heating

The cooling and heating of the shelves depend on the circulation of the heat conducting fluid in the circulation system. The temperature lowering of the heat conducting fluid is realized by direct evaporation of the refrigerant at a stainless plate-type heat exchanger. The heating of the heat conducting fluid is done by a stainless heat exchanger. The heat conducting fluid used is of low viscosity silicon oil, the heat conductivity, cryogenic performance and chemical stability of which is very good. The circulation pump forces the heat conducting fluid to circulate.

Freeze Dryer Vacuum System unit

The vacuum system can match the sublimation temperature of the condenser, over or under vacuum will go against sublimation. The precondition of vacuum control is the system can keep the lowest leakage; the vacuum pump can be power enough with power preservation.
The vacuum is composed of drying chamber, vacuum pipe, and vacuum measurement system.

Freeze Dryer Shelf up-down System

The hydraulic pump unit and hydraulic cylinder are mounted on the top of the Drying Chamber. Driven by the hydraulic pump, the hydraulic cylinder makes the shelf lifting freely inside the box to facilitate the feeding the product substance, delivery of the product as well as cleaning. The piston-rod is sealed by the silicon rubber O-ring, which ensure non-leakage and therefore, no contamination to the product being prepared. The electromagnetic direction valve and hydraulic balancing valve response quick and accurate, which ensure the stability and smooth movement without sliding and vibration.

Freeze Dryer Control and control System

Fully-automatic programmed operation system, and with manual or emergency control system.
Display real time status of all elements of the system.
Display real time operation information and error alarm message.
Display freeze drying processes parameter.
Store and deal with operation data.
Display real time and history processes parameters trend.
Eliminate possible operational mistake.
Forbidden unauthorized operation.
Collect batch-related information.
Prepate for freeze drying processes report.

Freeze Dryer SIP (Sterilization In Place)

SIP system is consist of tubes,valves and filter set. Tubes is stainless steel AISI 316L. Valves is Germany BURKERT. Filter set is USA PALL.

Sterilization condition:121?,30min, F0 is 8.

Conform to cGMP or FDA and provide related validation meterials.

Freeze Dryer CIP (Cleaning In Place)

CIP system is for cleaning chamber and ice condenser.No dead corner exist during cleaning. CIP system consist of nozzle,nozzle ball,valves and pump etc.. Nozzles is stainless steel AISI 316L.(USA SSC Co.,).Pump is Germany nash-elmo. Valves is Italy Verbia. Manual setting cleaning parameters is applicable whole course. And conform to GMP and FDA regulations and provide system validation material.

Freeze Dryer Parameter meter

Refrigerating system:
Compressor is Germany BITZER or COPELAND.Refrigerant is R404A/R22,Other is ALCO.DANFOSS.Vaccum system:Vaccum pump is Britain Edwards or Germany LEYBOLD and Japan ULVAC.Chamber-Condenser Insulation Valve is Hydraulic Mushroom Valve.Vaccum Valve is USA.KEYSTONE Butterfly Valve and Italy VERBIA ballValve.Liquid Circulation System:Circulation Pump is Germany WILO.Intermediate Heating Transfer Fluid is Low Viscosity Silicon Oil.Heating Exchanger is Sweden ALFALAVAL or SWEP.