New Type High-Quality and High-Yield Full Auto-Production Linked Line with Washing Machine, Oven, Filling and Capping Machine is specially designed to produce oral liquid bottles.It is accorded with G.M.P. standard. It is consists of Model QCLX40 Vertical Washing Machine, Model GMSU-400W Tunnel with Mesh-Belt type Sterilizing Oven, Model KGZ8 Oral Liquid bottle Filling and Capping Machine. It is equipped with advanced instruments which are produced both inside and outside the country and features high productive capacity, high technology quality, stable and reliable function and beautiful outward. It is suitable to produce the oral liquid of various specifications. It can complete some process-steps such as ultrasonic coarse washing; the washing and spraying alternately using water and steam; drying and sterilizing; filling and capping etc. The unit equipment which is composed this linked line may be use solitarily.
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Major Equipments: |
1. Model QCLX40 Vertical Ultrasonic Bottle washing Machine
2. Model GMSU-400W Tunnel with Mesh-Belt Type Sterilizing Oven
3. Model KGZX8 Oral Bottle Filling and Capping Machine
Suitable specification: For New Type Oral Liquid bottles of 5-25ml
Satisfies the quality requirements of G.M.P.
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The Schematic Diagram of Full Auto-production Linked Line with Washing Machine, Oven, Filling and Capping Machine for New Type Oral Bottle. |
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Operating Principle:
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The bottles in bulk are putted into ultrasonic washing tank by the bottle-arranging tray. After ultrasonic washing for about 80 seconds, the bottles are fed to lifting driver wheel by bottle feeding spiral conveyer and into a big drum and clamped by a manipulator, and turn over 180 o (bottle's mouth downward) and clockwise rotated along with the big rotating disk 6 groups jet pipes which equipped with jet needles and under the lower of big rotating disk tracks and inserts the jet needles into the bottles and completes the spraying for inside bottles according to the procedures; spraying for two times using circulating water; spraying for once using compressed air; spray for once using fresh water; spraying for two times, using purifying compressed air again. Meantime, completes the spraying for outside bottles, so far, the washing technology for the bottles is completed. Washing bottles turn over for 180 o again (bottle's mouth upward) by a manipulator and fed into a tunnel type oven by driving wheel. The bottle washing machine can control the productive capacity by frequency conversion and speed change function, and can control and adjust the sequential coordination of each procedure by PLC program control function.
The close-packed bottles are fed into the tunnel with mesh-belt type sterilizing oven and into the preheat area by the conveying mesh-belt. And then, the bottles are passed the high temperature area (sterilizing area) and the cooling area. Finally, the bottles are passed the laminar flow area, and completed the sterilizing process. Then, the bottles are fed out from the oven and fed into the oral liquid filling and capping machine. The heating process of the bottles is carried out by gold-plated quartz heat pipe which is on the upper of the mesh-belt and the stainless steel heat pipe which is on the lower of the mesh-belt. In the high temperature area, the bottles are undergoed drying and sterilizing process over 4 min. The speed of mesh-belt is controlled by machine type stepless speed changer. In order to prevent contamination, in whole sterilizing process, the bottles are under the protection of a 100 stage laminar flow protection device. Both front and rear laminar flow protection device are consisted of medium-efficiency blower fan and high-efficiency filter. The cooling process of the bottles which to be fed out from the oven is carried out by the fan which is installed on the rear of the oven and can ensure the temperature of the bottles is ≤ 40 ℃.
The bottles are fed into the filling and capping machine by a guide and an adjustable pitch type screw bolt, and fed into filling tray with 8 stations by a driver disk which is clockwise rotated. The feed liquid is supplied by glass pump and lifting action. The bottles which already filled with feed liquid are fed into a clockwise rotating disk with 8 stations for cap-clamping by three reversible rotating disks. The aluminum caps (replace the rubber corks) are tracked and clamped on the bottle mouth by 8 flexible three tools type clamping chuck. Then, the aluminum caps (replace the rubber corks) are sequentially arranged by oscillating feeder, and fed on conveying belt by a guide and covered with the bottle mouth. After that, the bottles which filled with oral liquid and cap-clamped are fed out by an out-feed rotating disk and fed into an out-feeding tray. |
Major Technical Parameters of Unit Equipments: |
1. Model QCLX40 Vertical Ultrasonic Bottle washing Machine |
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Description:
Model QCLX40 Ultrasonic Type Washing Machine is applied is applied to wash ampoules, Penicillin bottles, infusion bottles etc. which outside diameter all are Ф10-30mm.
■ Washing quality satisfies the GMP standard.
■ Simple and Practical operation is due to the mode of bottle feeding is in bulk
■ Mode of bottle clamping using manipulator can be use for multi-specifications bottles
■ Adopted the modes of tracking and inserting for washing using water and gas to ensure bottle washing quality and low consumption of water and air
■ Adopted PLC control and touch Screen for display and operation.
■ Can Supply GMP verification documents and give assistance for that pass GMP verification. |
Operating Theory:
The bottles in bulk are putted into ultrasonic washing tank. After ultrasonic washing for about 8 seconds, the bottles are fed to lifting driver wheel by bottle feeding spiral conveyer and into a big drum and clamped by a manipulator, and turn over for 180(bottle mouths downward) and clockwise rotated along with the big rotating disk. 6 groups jet pipes which equipped with jet needles and under the lower of big rotating disk tracks and inserts the jet needles into the bottles and completes the spraying for inside` bottle according to the Procedures: Spraying for two times, using circulating water; spraying for once, using compressed air; spraying for once, using fresh water; spraying for two times, using purifying compressed air again. Meantime completes the spraying for outside bottles, so far, the washing technology for the bottles is completed. Washed bottles turn over for 180 again (bottle mouths upward)by manipulator and fed into a tunnel type oven by drive disk .This machine can control the productive capacity by frequency conversion and speed change functions, and can control and adjust the sequential coordination of each procedure. |
Technical Data: |
Power Supply |
380V 50Hz |
Gross Power |
1.3kw |
Ultrasonic Power |
600W 27kHz |
Washing Range |
φ10－φ30mm(For Antibiotic Bottle and Oral Liquid Bottle etc.) |
Production Capacity |
12000 Bottles/h (Max) |
Air Pressure |
0.35-0.45Mpa |
Water Pressure |
0.3-0.4Mpa |
Water Consumption |
0.38m3/h |
Air Consumption |
30 m3/h |
Breaking Rate |
＜1% |
Weight |
About 2000kg |
Overall Size |
2070×2100×1300(mm)(L×W×H) |
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2.Model GMSU-400W Tunnel with Mesh-Belt Type Sterilizing Oven |
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Description:
Series GMSU 400 Tunnel Type Bacterium Killing Oven is suitable for the drying and sterilizing of antibiotic-bottles, ampoule (bottle）, oral liquid-bottles and infusion bottles.
■ CIP washing system in original site is first inside country.
■ Complete one hundred (100） stage laminar flow purifying device.
■ Advanced electronic control system.
■ Conveying wet is stable; conveying belt is step less speed change; speed can be displayed.
■ It has paper recording or non-paper recording in temperature control system.
■ The heating part is supplied with a gold-plating quartz pipes; the lower part is supplied with a stainless steel heating pipes.
■ Adopted digital to display and set heating temperature and automatically control display.
■ Satisfied 02D.3-1995 Pharmaceutical industry standard and met G.M.P. demand, it is mechanical-electronically combination machine.
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Operating Theory:
Under the monitoring of intelligent system, bottle are fed into preheating zone, high temperature killing bacterium zone (temperature is ≥ 350c; bacterium killing time is ≥ 5 min） and low temperature zone of tunnel bacterium killing oven. The speed of conveying belt is step less adjustable. It has paper recording or non-paper recording in temperature control system. Whole operating process always under the protection of 100-stage laminar flow.
Technical Data:
Power Supply |
380V 50Hz |
Gross Power |
≤30kw |
Range of Temperature Adjustment |
100-350ºC |
Transport Mode |
Mesh-Belt |
Conveying Speed |
60-220mm/min (Stepless Speed Adjustment) |
Laminar Flow Purifying Stage |
100 stage |
Cooling Mode |
100 stage Vertical Laminar flow cooling |
Air Volume of Purifying Blower Fan |
2250-3370m3/h |
Win Pressure |
200-300Pa |
Control of Wind Speed |
Speed Change by Frequency Converter |
Weight |
About 2200kg |
Unit Noise |
≤70dB |
Overall Size |
4880×1220×2050(mm）(L×W×H) (for unit equipment)
4880×1220×2050(mm）(L×W×H) (for on-line) |
Productive Capacity:
■ Tubular-Antibiotic bottle
2ml------15000 piece/hour 5ml------10000 piece/hour
7ml------- 8000 piece/hour 10ml------8000 piece/hour
20ml ----- 5000 piece/hour
■ Mold-Antibiotic bottles
5ml-----12000 piece/hour 7ml-------8000 piece/hour
10ml-----6000 piece/hour
■ Liquid oral bottles
10ml----10000 piece/hour 20ml------7500 piece/hour
■ Ampoule (bottles）
1ml-------20000 piece/hour 2ml------18000 piece/hour
5ml-------15000 piece/hour 10ml-----12000 piece/hour
20ml-------8000 piece/hour |
3.Model KGZX8 Oral Bottle Filling and Capping Machine |
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Descriptiob:
Model KGZX8 Oral Liquid Bottle Filling and Cap-clamping Machine is applied to fill and cap-clamp for oral liquid preparations of 5-25ml and other liquid, and it is a high capacity oral liquid filling and cap-clamping machine.
■ Satisfies the GMP standard
■ High output is due to fill and cap-clamp in 8 stations
■ Supplied with a device to ensure that failure to fill with shortage of bottles
■ Adopted PLC control and touch screen for display and operation
■ Adopted a speed control mode using frequency converter to control the productive capacity Can supply GMP verification documents and give assistance for that pass GMP verification |
Operating Theory:
The bottles are fed into the filling and cap-clamping machine by a guide and an adjustable pitch screw bolt, and fed into filling tray with 8 stations by a driver disk which is clockwise rotated. The feed liquid are supplied by glass pump and filled by that tracking for the syringe needle and lifting action. The bottles that already filled with feed liquid are fed into a clockwise rotating disk with 8 stations for cap clamping by three reversible rotating disks. The aluminum caps (replace the rubber corks) are tracked and clamped on the bottle mouth by 8 flexible three tools type clamping chuck. Then, the aluminum caps (replace the rubber corks) are sequentially arranged by oscillating feeder, and fed on the conveying belt by a guide and covered with the bottle mouth. After that, the bottles that filled with oral liquid and cap-clamped are fed out by an out –reed-rotating disk and fed into an out-feeding tray. |
Major Technical Parameters:
Power Supply |
380V 50Hz |
Suitable Specification |
5-25ml |
Gross Power |
2.2kw |
Productive Capacity |
100-200 Bottles/min |
Metering Error |
≤±2% |
Breaking Rate |
≤0.1% |
Filling Volume Range |
0.1-2.5g |
Qualifying Rate of Capping and Sealing |
≥98% |
Gross Weight |
About 1300kg |
Overall Size |
2850×1400×2000(mm)(L×W×H) |
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Major Technical Parameters of Production Line:
Suitable Specification |
5-25ml |
Productive Capacity |
12000 Bottles/h (per 10ml; Max) |
Metering Error |
≤±2% |
Breaking Rate |
≤0.1% |
Qualifying Rate of Capping and Sealing |
≥98% |
Gross Power |
36kw |
Gross Weight |
About 3500kg |
Overall Size |
9600×3800×2050(mm)(L×W×H) |
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Characteristics
■ Production capacity can up to 200 bottles/min.
■ The unpacked bottle-feeding mode of bottle washing machine make the operation becomes more simple and reliable.
■ In the bottle washing machine, the bottle capping mode which using a robot may be suitable various specifications.
■ The tracing and insert washing mode and the use of spraying by water and steam can ensure the washing quality and economize on water and steam.
■ This production line is supplied with a infrared radiometer heating type quartz pipe and a 100 stage laminar flow protection device which use for full process.
■ This production line is supplied with advanced imported instruments, and so, it's control system is advanced, sensitive, stable and reliable.
■ The mesh-belt of the oven is supplied with a function of washing in origing site, and can satisfy the washing requirement of G.M.P. standard.
■ A speed adjustment mode which using frequency converter can control the production capacity of this production line.
■ A interlock device of this production line can control the balanced production for three equipments of production line.
■ Each equipment of this production line is supplied with the PLC program controller, and whole operation process is may be display by touch screen.
■ This production line is supplied with a function which ensure that failure to fill with shortage bottle. We can supply G.M.P. verification documents and give a assistance to pass G.M.P. verification. |
Configuration:
NO |
Equipment Name |
Model NO. |
Origin |
1 |
Programmable Controller |
FXIS-30MR |
Japan |
2 |
Frequency Converter |
VFD015M434 |
Japan |
3 |
Man-Machine Interface |
INTECH |
Japan |
4 |
Man-machine Interface |
MT200D |
Japan |
5 |
Temperature Controller |
GCD-23AS/R |
Japan |
6 |
Indicating Light |
AD16 |
France |
7 |
Air Switch |
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France |
8 |
Water Pump |
CR5-8 |
Denmark |
9 |
Glass Pump |
20ml |
Shanghai |
10 |
Solenoid Valve |
ZCS20 DC24V |
Sino-foreign Joint venture |
11 |
Temperature Recorder |
EX-11-03, EL-23603 |
Sino-foreign Joint venture |
12 |
Adjustable Throttle valve |
G1/8” G1/4” |
Taiwan |
13 |
Ultrasonic Instrument |
XFQ600W 27KHz |
Shanghai |
14 |
Pressure Gauge |
60ZT 1Mpa |
Shanghai |
15 |
Stainless steel Heat Pipe |
380V 1500W |
Shanghai |
16 |
Speed Reducer with Stepless Speed Adjustment |
BWE1812 |
Shanghai |
17 |
Three-Phase Solid-state Relay |
GJH |
Shanghai |
18 |
Blower Fan (Air-In) |
YDF-2.24A-4s,DF-2.8 |
Nanjing |
19 |
Gold-Plated Quartz Heat Pipe |
380V 50Hz |
Shanghai |
20 |
High-Temperature and High-Efficiency Filter |
GK,GKW(may be a imported one) |
Suzhou |
21 |
Push-Button |
La39 |
Japan |
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