Full Auto-Production Linked Line with Washing Machine, Oven, Filling Machine for Penicillin Bottles of 2-100ml
Description:
Full Auto-Production linked Line with Washing Machine, Oven, Filling Machine is specially designed to produce freezing-drying medicines, liquid injections and infusion injections.It is accorded with G.M.P. standard. It is consists of Model XCQ-IV Ultrasonic Bottle Washing Machine (coarse washing), XCQ-VI Ultrasonic Bottle Washing Machine (fine washing), Model GMSU-400W Tunnel with Mesh-belt Sterilizing Oven, Model HGS Liquid Filling and Cork-Putting Machine, Model GG Supply Water Filtering Device, and 100 Stage Laminar Flow Protective Cover. It is equipped with advanced instruments which are produced both inside and outside the country and features stable function, high automatization, stable functions, low noise, convenient commission maintenance. It is suitable to produce the antibiotic bottles and infusion bottles of various specifications. The unit equipment which is composed this linked line may be use solitarily.
Whole productive process of this production line is under the protection of a 100 stage laminar flow protective cove, and the production quality is accorded with G.M.P. Standard, and passed Quality Certificate from British ITS Company.
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Major Equipments:
1. Model XCQ-IV Ultrasonic Bottle washing Machine (coarse washing)
2. Model XCQ-VI Ultrasonic Bottle washing Machine (fine washing)
3. Model GG Feed Water Filtering Device
4. Model GMSU-400W Tunnel with Mesh-Belt Type Sterilizing Oven
5. Model HGS Liquid Filling and Cork-Putting Machine
6. A 100 Stage Laminar Flow Protective Cover
7. The Guide for Dut-Feeding Bottle
8. Transport Device
9. Specific Tray for Bottle
Suitable specification: For antibiotic bottle, infusion bottles and oral liquid bottles of 2-100ml.
Satisfies the quality requirements of G.M.P. Standard. |
The Schematic Diagram of the Production Linked Line with Washing Machine, Oven, filling Machine. |
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Operating Principle:
In coarse washing area, the tray full of antibiotic bottles is putted into Model XCQ-IV Ultrasonic Bottle Washing Machine and begins coarse washing. Under the control of PLC programmable controller, the tray is entered the flushing station and drenching station according to the procedures successively. Ultrasonic washing time is ≥ 25 seconds, and washing time may be set by PLC program and adjustable freely. Internal flushing is thrice circle washing by water and steam, and it's time and times may be set by PLC program and adjustable. In flushing station, the rotary disk is turned over 180° , and put all bottles into the water to washing by ultrasonic wave. After the completion of washing procedure per prescribed time, the rotary disk is turned over 180° again, and the tray is putted into the drenching station by putting disk. In drenching station, the lifting device lifts and down automatically, and the needle pipes are inserted into all bottles and the thrice water and steam circle washing is began. The washing for external wall of the bottles is carries out by spraying device. After above procedure is finished, the bottles are entered fined washing area.
In fine washing area, the tray is entered Model XCQ-VI Ultrasonic Bottle Washing Machine and begin fine washing. Under the control of PLC programmable controller, the bottles is entered the flushing station and drenching station according to the procedures successively. The washing procedures are the same with one of Model XCQ-IV Ultrasonic Bottle Washing Machine. The Ultrasonic washing is time ≥ 25 seconds, and the washing time may be set by PLC program and adjustable freely. Internal flushing of the bottles is thrice circle washing by water and steam, and flushing time and times may be set by PLC program and adjustable freely. After the completion of washing procedures, the tray is putted into the separate station of washing machine automatically and is carried out the separation. Blank tray comes back the coarse washing area, and washed-up bottles in bulk are entered the Tunnel Type Sterilizing Oven automatically.
In Model GMSU-400W Tunnel with Mesh-Belt Type Sterilizing Oven, under the monitoring of intelligence system, the bottles which along with the mesh-belt are successively entered the preheating area, high temperature sterilizing area (monitoring temperature of the probe is ≥ 350℃, sterilizing time is ≥ 5 min), and low temperature cooling area. The speed of mesh-belt are stepless adjustable. The temperature monitor system is supplied with the function of paper recording or non-paper recording. Then, the dried and non-funguses bottles are entered the liquid filling and cork-putting machine and began accurate filling and cork-putting.
The dried and non-funguses bottles are fed into the mesh-belt of Model HGS Liquid Filling and successively fed into the conveying rotary disk. Then, these bottles are intermittently fed into the "U" type chamfer of dividing disk which dividing rotary by the driving of duplex chain type mesh-belt. The dividing disk is clockwise rotated intermittently. The bottles are respectively filled and corked at the same time on the station of 30° and 90° .After that the bottles are intermittently rotated under the action of the guide, and fed into the guide for out-feeding bottle. Whole operation process is under the protection of 100 stage purifying laminar flow protection device. An imported peristaltic pump filling system is installed in the filling machine.
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Major Technical Parameters of Unit Equipments: |
| 1.Model XCQ-IV Ultrasonic Bottle Washing Machine |
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Description:
Model XCQ-IV Ultrasonic Bottle type washing machine is specially used for washing of antibiotic-bottles, oral liquid-bottles and infusion bottles, their size range is 2-100 ml.
• Simple structure, stable function, easy operation and low maintenance cost.
• Multi-specifications, multi-applications.
• Can operate with combination line or independent.
• Adopted pneumatic system; non-pollution and low noise.
• Adopted PLC control and man-machine control interface for bottle washing process; ultrasonic washing time can be set freely.
• Washing with plate carrying ort low breaking rate of washing bottles.
• Washing quality satisfies the G.M.P. verification documents and gives assistance for pass G.M.P. verification.
• We can supply G.M.P. verification documents and give assistance for pass G.M.P. verification. |
Operating Theory:
Place bottles in the special tray; put the tray into the turn over device. Press the start button. The tray turns over for 180°under the auto-control of man-machine interface using PLC programmable controller. Put all bottles into the water to be washing by ultrasonic wave, then turn over another 180° after 25 seconds; put the tray into flushing and drenching station. The tray down automatically by lifting device; needle pipes inserted into all bottles to carry out three times circle washing by water and steam for intimae wall of bottles. The washing for extremely wall is finished. The bottles along with the tray withdraw from the washing machine .All process time is 78 seconds in total. Next washing for bottles on the tray needs once circle only. |
Main Technical Parameter:
Power Supply |
380V 50Hz |
Gross Power |
1.2kw |
Ultrasonic Power |
1000W 27kHz |
Scope of washing |
2-50 ml Antibiotic bottle, Liquid oral bottle etc. |
Water Pressure |
0.3-0.4Mpa |
Air Pressure |
0.35-0.45Mpa |
Water Consumption |
10 liter per plate ( 2 ml Antibiotic bottle) |
Breaking Rate |
≤0.1% |
Noise |
≤70dB |
Weight |
About 600kg |
Overall Size |
1510×1330×1705(mm)(L×W×H) |
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Productive Capacity:
Tubular-Antibiotic bottle
2ml------20000 piece/hour 15ml------12000 piece/hour
5ml------16000 piece/hour 20ml------- 7000 piece/hour
7ml------12000 piece/hour 100ml------ 2200 piece/hour
10ml-----12000 piece/hour
Mould-Antibiotic bottle
5ml------16000 piece/hour 7ml------12000 piece/hour
12ml-----12000 piece/hour 50ml------2200 piece/hour
Liquid Oral bottle
10ml-----13000 piece/hour 20ml-----10000 piece/hour |
2. Model XCQ-VI Ultrasonic Type Bottle Washing Machine |
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Description:
Model XCQ-VI Ultrasonic bottle type washing machine is specially used for washing of antibiotic-bottles, oral liquid-bottles and infusion bottles; their size range is 2-100 ml.
■ Simple structure, stable function, easy operation and low maintenance cost.
■ Multi-specifications, multi-applications.
■ Can operate with combination line or independent.
■ Adopted pneumatic system; non-pollution and low noise.
■ Adopted PLC control and man-machine control interface for bottle washing process; ultrasonic washing time can be set freely.
■ Washing with plate carrying ort low breaking rate of washing bottles.
■ Washing quality satisfies the G.M.P. verification documents and gives assistance for pass G.M.P. verification.
■ We can supply G.M.P. verification documents and give assistance for pass G.M.P. verification. |
Operating Theory:
Place bottles in the special tray; put the tray into the turn over unit to inject water into bottles. Press the start button. Under the control of Auto-Procedures, the tray turn 180° put all the bottles into the water, to be washing by ultrasonic, then turns another 180° after 25 seconds; put the tray into flushing and drenching station. Lift set going up automatically, insert the needle-pipes into bottles to carry out three times circle-steam washing inside wall. Spraying unit washing the outside of the bottle. Then these bottles are putted into segregation unit, bottles are segregated automatically from plate, and bottles are putted into tunnel bacterium killing oven in bulk. Bottles are putted into tunnel bacterium killing oven in bulk. Bottle-tray withdraws from the washing system by push-cylinder. All process time is 78 seconds in total, and every program can be adjusted in time. Then next circle is according to this also. |
Main Technical Parameter:
Power Supply |
380V 50Hz |
Gross Power |
1.5kw |
Ultrasonic Power |
1000W 27kHz |
Water Pressure |
0.3-0.4Mpa |
Air Pressure |
0.35-0.45Mpa |
Scope of washing |
2-100 ml Antibiotic bottle, Liquid oral bottle etc. |
Water Consumption |
10 liter per plate ( 2 ml Antibiotic bottle) |
Breaking Rate |
≤0.1% |
Noise |
≤70dB |
Weight |
About 1200kg |
Overall Size |
1700×1250×1700 (mm)(L×W×H) |
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Productive Capacity:
Tubular-Antibiotic bottle
2ml------20000 piece/hour 10ml------12000 piece/hour
5ml------16000 piece/hour 20ml------- 7000 piece/hour
7ml------12000 piece/hour 150ml----- 2200 piece /hour
Mould-Antibiotic bottle
5ml------16000 piece/hour 7ml------12000 piece/hour
12ml----12000 piece/hour 50ml------2200 piece/hour
Liquid-Oral bottle
10ml----13000 piece/hour 20ml-----10000 piece/hour |
3. Model GMSU-400W Tunnel with Mesh-Belt Sterilizing Oven |
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Description:
Series GMSU 400 Tunnel Type Bacterium Killing Oven is suitable for the drying and sterilizing of antibiotic-bottles, ampoule (bottle), oral liquid-bottles and infusion bottles.
■ CIP washing system in original site is first inside country.
■ Complete one hundred (100) stage laminar flow purifying device.
■ Advanced electronic control system.
■ Conveying wet is stable; conveying belt is step less speed change; speed can be displayed.
■ It has paper recording or non-paper recording in temperature control system.
■ The heating part is supplied with a gold-plating quartz pipes; the lower part is supplied with a stainless steel heating pipes.
■ Adopted digital to display and set heating temperature and automatically control display.
■ Satisfied 02D.3-1995 Pharmaceutical industry standard and met G.M.P. demand, it is mechanical-electronically combination machine. |
| The Schematic Diagram of GMSU-400W Tunnel with Mesh-Belt Sterilizing Oven |
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Operating Theory:
Under the monitoring of intelligent system, bottle are fed into preheating zone, high temperature killing bacterium zone (temperature is ≥ 350℃; bacterium killing time is ≥ 5 min) and low temperature zone of tunnel bacterium killing oven. The speed of conveying belt is step less adjustable. It has paper recording or non-paper recording in temperature control system. Whole operating process always under the protection of 100-stage laminar flow. |
Technical Data:
Power Supply |
380V 50Hz |
Gross Power |
≤30kw |
Range of Temperature Adjustment |
100-350ºC |
Transport Mode |
Mesh-Belt |
Conveying Speed |
60-220mm/min (Stepless Speed Adjustment) |
Laminar Flow Purifying Stage |
100 stage |
Cooling Mode |
100 stage Vertical Laminar flow cooling |
Air Volume of Purifying Blower Fan |
2250-3370m3/h |
Win Pressure |
200-300Pa |
Control of Wind Speed |
Speed Change by Frequency Converter |
Weight |
About 2200kg |
Unit Noise |
≤70dB |
Overall Size |
4880×1220×2050(mm) (L×W×H) (for unit equipment)
4880×1220×2050(mm) (L×W×H) (for on-line) |
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Productive Capacity:
■ Tubular-Antibiotic bottle
2ml------15000 piece/hour 5ml------10000 piece/hour
7ml------- 8000 piece/hour 10ml------8000 piece/hour
20ml ----- 5000 piece/hour
■ Mold-Antibiotic bottles
5ml-----12000 piece/hour 7ml-------8000 piece/hour
10ml-----6000 piece/hour
■ Liquid oral bottles
10ml----10000 piece/hour 20ml------7500 piece/hour
■ Ampoule (bottles)
1ml-------20000 piece/hour 2ml------18000 piece/hour
5ml-------15000 piece/hour 10ml-----12000 piece/hour
20ml-------8000 piece/hour |
| 4. Model HGS Liquid Bottle Filling &Corking Machine |
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Description:
Model HGS Liquid Bottle Filling & Corking Machine is the new generation machine, which is developed by our technicians who referred to advanced technique of foreign countries. It is suitable for medicine bottle of 2-100 ml antibiotic-bottle, infusion bottle. It features advanced control instruments, accurate filling, stable function, good out-face, so that, it is ideal filling corking machine for liquid injection and freeing-drying medicines.
■ Imported filling system with peristaltic pump has high filling accuracy.
■ Have complete one hundred (100) stage laminar flow purifying protection systems.
■ Supplied with a device which ensures that failure to fill with shortage of bottles.
■ Have a device which ensures automatically account.
■ Adjust speed by frequency conversion.
■ Satisfies the G.M.P. standard. We can supply G.M.P. verification documents and give assistance for pass G.M.P. verification. |
The Schematic Diagram of Model HGS Liquid Bottle Filling &Corking Machine
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Operating Theory:
After killed bacterium and desiccated bottles are fed into the conveying disk and into u-chamfer of dividing disk which clockwise rotate intermittently. The bottles are filled and corked at the same time on two stations of 30 and 90. After that, Bottles are rotated intermittently under the action lf guide and fed into guide of out–feeding tray. All operation of one hundred (100) stages purifying laminar flow. An imported peristaltic pump filling system is adopted on filling equipment. |
Main Technical Parameter:
Power Supply |
380V 50Hz |
Gross Power |
1.5kw |
Purifying Stage |
100 Stage |
Method of filling |
creed-pump |
Error of bottling Quantity |
≤±2% |
Speed Control |
frequency conversion speed adjustment. |
Noise |
≤70dB |
Gross Weight |
About 700kg |
Overall Size |
1200×900×2050(mm) (L×W×H) |
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Productive Capacity:
4000------5000 piece/hour (2-10ml) |
5.Model GG Supply Water Filtering Device
Power Supply |
380V 50Hz |
Gross Power |
1.5kw |
Water Pressure |
0.3-0.4Mpa |
Water Filtering Accuracy |
0.45μm |
Overall Size |
1100×600×1200(mm)(L×W×H) |
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Major Technical Parameters of Production Line
For Antibiotic Bottle (Tubular Type)
2-25ml |
10000 Bottles/h |
7-10ml |
10000 Bottles/h |
15-20ml |
7500 Bottles/h |
For Antibiotic Bottle (Mould Type)
50ml |
2000 Bottles/h |
100ml |
800 Bottles/h |
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Full Auto-Production linked Line with Washing Machine, Oven, Filling Machine Characteristics:
■ Whole production line is under the protection of 100 stage laminar flow purifying device, and this is accord with G.M.P. Standard.
■ The fan with 100 stage laminar flow is supplied with a function of frequency conversing speed change, and it can kep optimum state of production environment.
■ This production line is equipped with advanced instruments which are produced at home and abroad; The control system is advanced and sensitive; It's function is stable reliable; The operation is more easy.
■ It is suitable for antibiotic bottle, oral liquid bottle and infusion bottle etc. of various specifications.
■ This production line is equipped with both stations of coarse washing and fine washing, and so, it can ensure the washing quality.
■ The mode of tray type washing can realize low bottle-breaking rate, and the breaking rate is ≤0.1%.
■ The bottle washing machine is supplied with washing technology mode which using PLC control and man-machine interface operation, and the ultrasonic washing time may be set freely.
■ The bottle washing machine is supplied a pneumatic system, and it is non-pollute and low noise.
■ In the tunnel type oven, the CIP washing system in original site is first inside country.
■ In the tunnel type oven, the temperature monitor system is equipped with some functions such as the control of temperature setting and display with paper recording or non-paper recording etc..
■ The speed of conveying belt of the tunnel type oven is stepless adjustable and satisfy various quality requirements.
■ This production line is equipped with a Britain's peristaltic pump type filling system, it make the filling accuracy raise, and the error of filling volume is ±2%.
■ The liquid filling and corking machine is equipped with a function of frequency conversing speed change.
■ The liquid filling and corking machine is equipped with a function of that failure to fill with shortage of bottles and is equipped with a function of auto-count.
■ This production line features convenient assembly, compact and rational mechanism, small floor space, and may be used as unit equipment.
■ This production line features beautiful outward, practicality, convenient commission and maintenance, low maintenance cost.
■ According to the requirement of user, Model GMSU Oven and HGS Filling and Sealing Machine may be equipped with touch screen operation mode.
■ We can supply G.M.P. verification documents and give a assistance to pass G.M.P. verification. |
Full Auto-Production linked Line with Washing Machine, Oven, Filling Machine Configuration:
NO |
Equipment Name |
Model NO. |
Origin |
1 |
Programmable Controller |
FXOS-30MR |
Japan |
2 |
Frequency Converter |
DV700 0.75KW 220V |
Japan |
3 |
Man-Machine Interface |
PWS 500S |
Taiwan |
4 |
Temperature Controller |
GCD-23AS/R |
Japan |
5 |
Indicating Light |
AD16 |
France |
6 |
Air Switch |
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France |
7 |
Micro-differential Pressure Meter |
Series 2000 |
U.S.A |
8 |
Water Pump (Feed Water Device) |
CR5-8 |
Denmark |
9 |
Peristaltic Pump |
505DZ/RL |
Britain |
10 |
Electromagnetic Reversing Valve |
4V210-08 DC24V |
Taiwan |
11 |
Solenoid Valve |
ZCS20 DC24V |
Sino-foreign Joint venture |
12 |
Temperature Recording |
EX-11-03, EL-23603 |
Sino-foreign Joint venture |
13 |
Air Cylinder |
IQG, BGW |
Shanghai |
14 |
Adjustable Throttle valve |
G1/8” G1/4” |
Taiwan |
15 |
Ultrasonic Wave Instrument |
XFQ1000W 27KHz |
Shanghai |
16 |
Pressure Gauge |
60ZT 1Mpa |
Shanghai |
17 |
Stainless steel Heat Pipe |
380V 1500W |
Shanghai |
18 |
Speed Reducer with Cycloid Pin Gear |
BWE 1812 |
Shanghai |
19 |
Direct-Current Speeder |
ZKS 0.5KW |
Shanghai |
20 |
Solid-State Relay |
H3100 EK |
Beijing |
21 |
Electromagnetic Dog. Coupling |
DLYD-16 |
Tianjing |
22 |
Blower Fan (Air-In) |
YDF-2.24A-4S,DF-2.8 |
Nanjing |
23 |
Gold -Plated Quartz Heat Pipe |
380V 1500W |
Shanghai |
24 |
High-Efficiency filter |
GK, GKW |
Suzhou |
25 |
Push-Button |
La39 |
Japan |
26 |
Triplex Elements
(Filtering, Pressure Reduction, Lubrication) |
XFRL4 |
Taiwan |
27 |
Converter Motor |
CL28-400-755 |
Taiwan |
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